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What is the purpose of removing solvent under reduced pressure?
High efficient and protect thermosensitive sapmle are the purpose of removing solvent under reduced pressure, as we all know, under reduced pressure, the boiling point of the solution will go down, liquids can evaporize and boil off at low temperature, that means the solvents come off a lot faster when under reduced pressure than at atmospheric.
At the same time, you don’t need to heating the rotary evaporation
flask (charging with liquid sample) at high temperature, not only save your time, but also could protect the thermosensitive substance in sample. -
Generally, removing solvent
has three method:1. You could removing solvent
under atmospheric pressure,use open type evaporator, this is a very traditional or home use method to remove solvent.Because of its poor efficiency few people use this method.2. Rotary evaporator
is an economical solvent removing method, also most popular used in laboratories and own high reputations from global rotavapor
users. Equipped with vacuum pump makes whole solvent removing process finishing under reduced pressure, will highly improve your efficient. -
For laboratory / home use, digital manual lifting type is enough (automatic lifting is optional), for pilot / industry use (10L-100L) rotary evaporator
, automatic lifting and explosion proof is required. High efficient is not the only factors need to consider, experiment and your laboratory safe is also very important.3. Wiped film evaporator
is the most efficient method to remove the solvent, if your budget is enough, this method will save your time and labor cost.